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epi-ml (eml  (Millipore)


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    Structured Review

    Millipore epi-ml (eml
    Miniscreen for Epigenetic Regulators of FXN Silencing During Reprogramming
    Epi Ml (Eml, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/epi-ml+(eml/epi/pmc05155629-216-80-139
    Average 90 stars, based on 1 article reviews
    epi-ml (eml - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming"

    Article Title: Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming

    Journal: Stem Cells and Development

    doi: 10.1089/scd.2016.0147

    Miniscreen for Epigenetic Regulators of FXN Silencing During Reprogramming
    Figure Legend Snippet: Miniscreen for Epigenetic Regulators of FXN Silencing During Reprogramming

    Techniques Used: Concentration Assay, Methylation, CpG Methylation Assay



    Similar Products

    epi-ml (eml  (Millipore)
    90
    Millipore epi-ml (eml
    Miniscreen for Epigenetic Regulators of FXN Silencing During Reprogramming
    Epi Ml (Eml, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/epi-ml+(eml/epi/pmc05155629-216-80-139
    Average 90 stars, based on 1 article reviews
    epi-ml (eml - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Miniscreen for Epigenetic Regulators of FXN Silencing During Reprogramming

    Journal: Stem Cells and Development

    Article Title: Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming

    doi: 10.1089/scd.2016.0147

    Figure Lengend Snippet: Miniscreen for Epigenetic Regulators of FXN Silencing During Reprogramming

    Article Snippet: DMSO, dimethyl sulfoxide; NaB, sodium butyrate; OSKM, Oct3/4, Sox2, Klf4, c-myc transcription factors. table ft1 table-wrap mode="anchored" t5 Table 1. caption a7 Compound (abbreviation) Target Process Concentration HDAC inhibitor 4b (4b) a HDAC3 Histone acetylation 5 μM Sodium butyrate (NaB) HDAC class I Histone acetylation 0.5 mM Tranylcypromine, Parnate (Par) LSD1 Histone H3K4 methylation 4 μM Tubastatin A (TubA) HDAC6 Histone acetylation 5 μM RG108 (RG) DNMT CpG methylation 5 μM BIX01294 (BIX) G9a Histone H3K9 methylation 4 μM Epi-ML (EML) b Multiple Multiple targets 5 μM DMSO Control — — Open in a separate window Only compounds that resulted in successful establishment of iPSC clones are shown. a HDACi 4b has been demonstrated to increase expression of the FXN gene in FRDA lymphoid cells and neurons, but not in FRDA fibroblasts or iPSCs. b Epigenetic Multiple Ligand (Epi-ML; Calbiochem) is a cell-permeable bis -arylidene compound that inhibits several mammalian histone-modifying enzymes, including SET7, PRMT1, p300/CBP, and SIRT1/2.

    Techniques: Concentration Assay, Methylation, CpG Methylation Assay